Betnovate N cream is used for the treatment of certain kinds of skin infections. It is the combination of two drugs, that is Betamethasone and Neomycin, belonging to two different classes with different mechanisms of actions.
It also includes anti-microbial action in its pocket. Betamethasone is a corticosteroid drug whereas Neomycin is an antibiotic used for treating skin infections against bacteria, fungus, and even viral infections.
As both drugs belong to different classes of medication so definitely they will have different mechanisms of action. So, let’s proceed further and explain about both drugs’ mechanisms of action.
Betamethasone: It is the adrenocortical steroids belonging to the category of glucocorticoids which works by controlling the protein synthesis rate and also controls the migration of polymorphonuclear leukocytes and fibroblasts.
It inhibits the activity of phospholipase A2 activity and also works by decreasing prostaglandins and leukotrienes formation in local tissues. It reduces the permeability of the capillaries and thereby prevents or reduces inflammation at the site of application.
Its therapeutic action works by decreasing tissue response at the inflammatory site. It is rapidly absorbed through PO administration.
Neomycin: It is an antibiotic medication belonging to the class of aminoglycosides. It controls or inhibits protein synthesis of bacteria and thus inhibits its replication and DNA synthesis. In simple terms it has a bactericidal effect against gram-negative bacteria.
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Overview
Overview Betnovate N Cream
Uses
Betnovate N Cream Uses
Betnovate N cream has various uses against many types of infections and inflammation. The uses include:
- Anti-inflammatory action
- Anti-pruritic activity
- Vaso-constrictive activity
- Psoriasis (scaly patches over skin)
- Eczema (itchy and dry skin)
- Atopic dermatitis
- Discoid eczema
- Miliaria
- Insect bite reactions
- Anal and intertrigo
- Otitis externa
- Prurigo nodularis
- Lichen simplex chronicus (neurodermatitis)
- lichen planus
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Drug Cost
Betnovate N Cream Cost in India
The cost of drugs varies from brand to brand and also on the quantity of cream tube one is purchasing. Talking about average price, it includes about Rs 48/- for 20g cream.
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Benefits and Side-effects
Side-effects of Betnovate N Cream
Side-effects
- Acne seems like erupting pimples
- Burning sensation
- Thinning of skin epidermis
- Skin colour change
- Hypertrichosis
- Skin redness
- High levels of bilirubin
- Rashes
- Itching
- Inflammation on skin
- Skin pigmentation
- Might face abnormalities in production of blood cells
- Unusual eyes sensation
- Skin dryness
- Local irritation
- Symptoms of hypercortisolism
- Striaea
- Telangiectasia
- Skin atrophy
- Secondary infection chances
- Perioral dermatitis
- Allergic contact dermatitis
- Skin maceration
- Easy bruising
- Hypopigmentation
- Fungal and bacterial infections
Systemic adverse effects include Cushing’s syndrome. Infants and children are highly susceptible to Adrenal pituitary suppression.
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Composition
Betnovate N Cream Composition
Betamethasone Valerate I.P………….. 0.10% w/w
Neomycin sulphate……………………0.5% w/w
Chlorocresol I.P……………………….0.1% w/w
(as preservative) in a non-greasy base.
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Substitute
Betnovate N Cream Substitute
There are many alternates available in the market which can be used if this Betnovate N cream is not available due to some reasons:
- Betamethasone cream
- Fucibet cream
- Fucidin cream
- Hydrocortisone cream
- Eumovate cream and ointment
- Adex gel
- Neomycin cream
- Aveeno cream
- Elocon
- Fluocinolone acetonide
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Safety Advice
Betnovate N Cream Safety Advice
- Avoid extensive use during pregnancy as it has been researched about side effects on developing babies.
- Check for the composition of the cream and if a patient is allergic to any of the drug components, refrain oneself from using it.
- It can be used by breastfeeding women but take care and avoid direct contact with the infant’s skin.
- There is no research evidence about interaction of alcohol with this drug but still avoid consuming alcohol as it may result in delay in wound healing.
- As this cream is used topically so no metabolism is done by kidney or liver, so it indicates that it is safe to the patients with liver and kidney problems.
- No interaction of cream with driving impairment, so means can be used safely.
- It is perfectly safe for hypertensive or hypotensive patients.
- Note that this ointment is not for treating pimples and acne, instead it will worsen the conditions
- This cream is also not recommended for skin pigmentation.
- Do not apply Betnovate cream to hypersensitive skin areas and also avoid applying directly to the face.
- Note that it is not a fairness cream. Many people get confused with this cream to be used for skin fairness and to reduce dark spots which is not its cup of tea.
- Ensure not to apply this cream over wounded, broken or damaged skin, it means that there should be no direct contact of skin into deeper tissues.
- Once you observe changes in treating your clinical condition, don’t stop it from using this cream, instead follow and complete the course of action to eradicate the problem fully.
- If you face any hypersensitive reactions, stop using the cream at that time only.
- If you are applying cream on eyelids, take precautions to avoid this cream entering into eyes, as it might result in glaucoma.
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Fact Box
Facts about Betnovate N Cream
Betnovate N Cream is accessible as an OTC (or over-the-counter) drug in some countries, while a prescription is required in others.
Acne or various non-inflammatory skin disorders should not be treated with the lotion.
Keep Betnovate N Cream at room temperature, shielded from direct sunlight and heat, and out of the reach of children.
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