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Augmentin 625

by Sheetal Verma

Augmentin 625 tablet is an antibiotic of penicillin type. The main function of the tablet is to help your body recover from infections caused by bacteria.

augmentin 625 uses benefits dosage side effects

It is generally prescribed as a cure for infections affecting the lungs, ear, throat, skin, soft tissue, and the urinary tract.

It contains amoxyxillin and clavulanic acid that destroy the toxic enzymes produced by bacteria and enhance the immunity of your body.

Tab Overview

Tab Augmentin 625 Overview

Tablet Uses

Uses of Augmentin 625

The primary use of the medicine is to fight infectious bacteria in the respiratory tract, middle ear and sinus, soft tissue, and urinary tract.

Tablet uses in india

It is also helpful in preventing dental and bone infections. Viral infections, however, cannot be cured by the Augmentin 625 medicine.

Do not start your Augmentin 625 tablets course without your doctor’s prescription.

Dose

The Augmentin 625 medicine is prescribed to be taken along with a meal, to avoid having an upset stomach. While it is not fatal to take it on an empty stomach, the potassium absorption in your body works better when taken with a meal.

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The best time to take the medicine is right before a meal, to avoid gastrointestinal issues. Taking the medicine at regular intervals of equal time helps you take it without any miss.

Dosage for infants:

For newborn babies (not more than 12 weeks old) a dose of 30 mg/kg/day is preferred. Divide the dose and give after every 12 hours. It is better to use the 125 mg per 5 ml oral suspension.

For babies over 12 months, again, the 12 hour interval is recommended. The 200 mg per 5 ml oral suspension should be given after every 12 hours. You can substitute it for 125 mg per 5 ml or 250 mg per 5 ml oral suspension.

For severe infections, 45 mg/kg/ day with 12 hour intervals, or 40 mg/kg/day with 8 hour intervals is the recommended dose.

For mild infections, a dose of 25 mg/kg/day with 12 hour intervals, or 20 mg/kg/day with 8 hour intervals is recommended.

Dosage for adults:

For mild infections in adults, the dose of one 500 mg tablet every 12 hours or one 250 mg tablet every 8 hours is ideal.

In case of severe infections or respiratory tract infections, one 875 mg tablet every 12 hours or one 500 mg tablet after every 8 hours is prescribed.

If the patient prefers to take the oral suspension instead of tablets, dosage can vary. 500 mg tablet can be substituted with 125 mg per 5 ml or 250 mg per 5 ml of the suspension.

The 875 mg dose for severe infections can be replaced with 200 mg per 5 ml or 400 mg per 5 ml of suspension.

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Dosage per day

For newborn babies (not more than 12 weeks old) a dose of 30 mg/kg/day is preferred. For severe infections, 45 mg/kg/ day with 12 hour intervals, or 40 mg/kg/day with 8 hour intervals is the recommended dose.

For mild infections, a dose of 25 mg/kg/day with 12 hour intervals, or 20 mg/kg/day with 8 hour intervals is recommended.

Take your medicines everyday as per your doctor’s prescription. Schedule your doses at equal intervals throughout the day. It is most common to take them before or after meal. Taking them on empty stomach can give you an upset stomach.

Dosage per kg

Pediatric patients (kids) with weights more that 40 kgs are given the same dosage as adults. Children with less than 40 kgs of weight should not be given the 250 mg tablet, give them the chewable tablets instead. This is because of the varying composition proportions of the normal tablets and chewable tablets.

How to use

The medicine should be taken as per the doctor’s prescription of dose and duration. Avoid chewing, crushing or breaking the tablet, take it as a whole. If unable to swallow the whole tablet, half the tablet and swallow both halves separately, one by one.

Before you start having your meal, gulp down the tablet with a glass of water. Space all your doses for a day at equal intervals, as per your doctor’s advice. Avoid storing the medicine at places where the sunlight reaches directly.

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Drug Cost

Augmentin 625 Cost in India

The cost written on the packaging of the Augmentin 625 tablets is Rs. 223 for every 10 tablets. The oral suspension comes for Rs. 39.89 per bottle of 30ml.

Benefits and Side-effects

Benefits and Side-effects of Augmentin 625

In the medical industry, every five benefits come with two side-effects. Listed below are some of the Augmentin 625 tablet benefits and side-effects.

side effects

Augmentin 625 Benefits:

The Augmentin 625 tablet serves a number of benefits, including cure to bacterial infections and anti-biotic properties.

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Cure bacterial infections- the tablet consists of amoxycillin, that fight the bacteria in your body. Along with this, it also contains Clavulanic acid that prevents the bacterial enzymes from destroying the amoxycillin. This combination is widely used as a treatment for bacterial infections in lungs, teeth, joints, bones, skin, and urinary tract.

The medicine has immediate effects on the bacteria and within two days, you start feeling better. However, you shouldn’t stop your course in between without completing it.

Immune body from potential infections- the clavulanic acid, apart from shielding the amoxycillin, also reduces the resistance of the bacteria against it. This enhances the effects of Amoxycillin on the bacteria.

Augmentin 625 Side-effects:

The side-effects caused by the Augmentin 625 tablets are mostly mild and do not require a visit to the doctor. They are only for a short time and go away soon. However, if the problems persist, you may consult your doctor.

Some of the common Augmentin 625 tablet side-effects are;

  • Diarrhea
  • Nausea
  • Indigestion
  • Weakness
  • Burning in the eyes
  • Loss of appetite
  • Vaginal discharge

Before you start your course of the Augmentin 625 tablet, inform your doctor about any allergies you have to antibiotics. The contents of the tablet can sometimes cause an allergic reaction in your body, which can lead to further health issues.

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Medicine Composition

Augmentin 625 Composition

The main contents of the Augmentin 625 tablets are amoxycillin and clavulanic acid. The amoxycillin is the active, bactericidal part of the antibiotic. It fights the bacteria by destroying the toxins produced by them to waken your system and damage the tissues.

medicine / drug / tablet composition

The clavulanic acid protects and boosts the amoxycillin against the bacteria. It contains the beta-lactamase enzyme that makes the amoxycillin more efficient. This results in better and faster destruction of the bacteria.

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The basic penicillin nuclues, 6 aminopenicillanic acid is the source of the amoxycillin. Fermenting the streptomyces clavuligerus produces the clavulanic acid.

Being a beta-lactam, it can inactivate some of the other beta-lactamase enzymes by blocking their active spots.

The composition of other ingredients varies in every form of the Augmentin 625 medicine.

  • Tablets- each tablet contains 0.63 mEq of potassium. Along with that, it comprises of Colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide.
  • Chewable tablets– these consist of colloidal silicon dioxide, flavorings, magnesium stearate, and mannitol. Among D&C Yellow No. 10, FD&C Red No. 40, glycine, sodium saccharin, and aspartame, any one is added to the composition of the tablets.
  • Oral suspension- it is a mix of Colloidal silicon dioxide, flavorings and xanthan gum. Another ingredient added is one among hypromellose, mannitol, silica gel, silicon dioxide, succinic acid, sodium saccharin, and aspartame.

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Tablet Substitute

Augmentin 625 Substitute

Never substitute augmentin tablets of higher mg with those of lower mg, or the other way round. For instance, substituting two 200 mg tablets with one 400 mg tablet does not mean the same dosage. The proportions of the ingredients in the composition are not the same in all of them.

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Alternatives

Various Augmentin 625 tablets substitutes are available in the market. Some of them are listed below along with their manufacturer and price details.

  • Moxikind-CV 625 Tablet by Mankind Pharma Ltd that cost ₹171/10 tablets.
  • Bactoclav 625 Tablet by Micro Labs Ltd come for ₹201.5/10 tablets.
  • Moxclav 625 Tablet by Sun Pharmaceutical Industries Ltd are priced ₹ 223/10 tablets.
  • Novamox CV 625mg Tablet by Cipla Ltd can be bought for ₹ 201.5/10 tablets
  • Clavidur 625 Tablet by Lupin Ltd are available for ₹ 194.5/10 tablets.
  • Hhamclav 625 Tablet by Hegde and Hegde Pharmaceutical LLP that cost ₹ 201.5/10 tablets.

Safety Advice

Augmentin 625 Safety Advice

Here are some tips and precautions that you must have in mind before beginning your course of the Augmentin 625 tablets.

When to take caution:

Patients with kidney or liver diseases should inform their doctor of their condition, beforehand. The doctor might have to adjust your dosage or prescribe your alternatives.

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Regular tests to monitor your liver functioning are required during your Augmentin 625 course. But it’s a big no-no for patients whose kidney diseases are severe.

Do not take the Augmentin 625 tablets if you’re already on a course of gout medicine, blood-thinner, anti-arthritis, anti-cancer, or drugs that prevent organ transplant.

Renally impaired patients sometimes need a reduced dosage, when their impairment is severe. They should not take the 875 mg Augmentin dose.

When is it unsafe:

The drug is not safe to take before any situation that needs you to drive. It’s side-effects include nausea, drowsiness and burning in the eyes, which can make you unable to drive.

After you’ve taken the Augmentin 325 tablets, avoid fat-rich foods in your meal. High-fat doesn’t let your body absorb the drug easily.

Also read: Side effects of nexito plus and its uses.

Patients with glandular fever and colitis should avoid taking the Augmentin 625 tablets. PKU patients should not use this medicine for treatment.

When is it safe:

Pregnant and breastfeeding women are generally not at any risk for consuming the Augmentin 625 tablets. If the doctor prescribes the tablet as safe, it is not harmful.

Human studies show that traces of the drug pass on to the breast milk, but not to a harmful extent.

Consumption of alcohol during your Augmentin 625 tablet course is considered safe.

Fact Box

Augmentin 625 Fact Box

  • Leaving the Augmentin 625 tablet course incomplete can cause adverse effects. The bacteria may resurface, and this time immune to the medicine. Complete the course, even if you feel like you don’t need the medicine anymore.
  • Keep your diet fat-free, eat home-cooked porridge, khichdi, dal, etc. Include whole grains, fluids and fibre-rich foods in your diet. They are easy to digest and restore good bacteria in your system.
  • After finishing your course, eat foods rich in probiotics, like yogurt, kimchi, kombucha, cheese, etc. The good bacteria in your gut can be restored by consuming probiotics. It reduces chances of diarrhea caused by antibiotics.
  • Diarrhea, as a side-effect, is nothing to worry, but cramps or bloody stools are not to be taken lightly. Immediately consult your doctor.
  • If you notice rashes or swelling as a side-effect of the medicine, stop the course right away. Inform your doctor and ask for alternatives or further treatment.
  • Even if the bacteria may have developed immunity against the antibiotic, the Augmentin 625 tablets can help fight them.
  • If you have any leftover medicine from your previous course, do not use it in the future. Get your doctor’s advice and prescription before you decide to take any antibiotic medicine.
  • Alcohol consumption is not unsafe during your antibiotics course but it can dehydrate your body and disturb your sleep cycle.
  • Taking the tablet in a sitting or standing position is recommended to avoid throat irritation. Do not sleep for 30 minutes after you’ve taken your medicine.
  • The Augmentin 625 tablets do not become a habit upon completing a full course.
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1 comment

Avi May 12, 2023 - 12:35 pm

It provides useful information. I appreciate the way it is written. Great article to read about.

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